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目的 探讨人工喂养与母乳喂养婴儿的免疫功能 ,为大力提倡母乳喂养提供理论依据。方法 对本市人工喂养 (n =2 2 0 )和母乳喂养 (n =2 60 )两组 4～ 6个月婴儿分别进行免疫功能检测 ,并调查半年内呼吸道感染发生率。结果 ①人工喂养组血清免疫球蛋白IgG ,IgM与母乳喂养组差异无显著性 (P >0 .0 5 ) ,IgA明显降低 (P <0 .0 1) ,IgE明显升高 (P <0 .0 1) ;人工喂养组静脉血CD3 + 与母乳喂养组差异无显著性 (P >0 .0 5 ) ,CD4 + 明显下降 (P <0 .0 1) ,CD8+ 明显升高 (P <0 .0 1) ,CD4 + /CD8+ 比值明显下降 (P <0 .0 1)。②人工喂养组呼吸道感染发生率较母乳喂养组明显升高 (P <0 .0 1)。结论 人工喂养婴儿免疫功能失调 ,更易患呼吸道感染。
Objective To explore the immune function of artificial feeding and breastfeeding infants, and to provide a theoretical basis for vigorously promoting breastfeeding. Methods The immune function of infants from 4 to 6 months in artificial feeding (n = 220) and breastfeeding (n = 2 60) in our city were respectively tested, and the incidence of respiratory infection in six months was investigated. Results ① There was no significant difference in serum immunoglobulin IgG, IgM and breastfeeding group between artificial feeding group and normal group (P> 0.05), IgA was significantly lower (P <0.01) and IgE was significantly higher (P <0. There was no significant difference between the CD3 + and the breastfeeding groups (P> 0.05), CD4 + (P <0.01) and CD8 + (P <0.01). 0 1), the ratio of CD4 + / CD8 + decreased significantly (P <0.01). ② The incidence of respiratory tract infection in artificial feeding group was significantly higher than that in breastfeeding group (P <0.01). Conclusion Artificial feeding infants immune dysfunction, more susceptible to respiratory infections.