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目的探讨芹菜对雌性小鼠动情周期的影响。方法对未处理的100只小鼠采用阴道脱落细胞涂片法观察动情周期。将动情周期规律的小鼠随机分为:对照组、低剂量组、中剂量组和高剂量组,对照组灌生理盐水、剂量组分别灌不同剂量的芹菜汁,每日观察动情周期。小鼠于灌胃7 d、14 d分批处死。结果灌胃14 d高剂量组小鼠动情前期较灌胃前明显缩短(P=0.002),动情后期则较灌胃前延长(P=0.018)。结论该剂量的芹菜汁可导致雌性小鼠的动情周期的紊乱。
Objective To investigate the influence of celery on estrous cycle in female mice. Methods Untreated 100 mice were treated with vaginal smear method to observe estrous cycle. Mice with estrous cycle were randomly divided into control group, low dose group, middle dose group and high dose group. The control group was infused with saline, and the dose group were given different doses of celery juice. The estrous cycle was observed daily. Mice in the stomach 7 d, 14 d partial death. Results The mice in the 14-day high dose group were significantly shorter than those in the control group (P = 0.002), while those in the late estrus period were prolonged (P = 0.018). Conclusion This dose of celery juice can lead to a disorder of the estrous cycle in female mice.