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本文通过放免法与LOwry法测量了兔眼角膜穿通伤后房水PGE2与总蛋白含量。结果:兔眼角膜穿通伤后1、3、8、24、48、72小时房水PGE2含量与正常值比较有非常显著性升高(P<0.01),到7天也未能降至正常(P<0.05);伤后1.3、8.24.48小时房水TP含量与正常值比较有非常显著性升高(P<0.01),但72小时后已降至正常(P<0.05)。我们认为:兔眼角膜穿通伤后PGE2.TP含量显著性升高,PGE2是BAB破坏的重要的炎症介质,TP是BAB破坏的结果。它们能代表损伤性炎症的严重程度。
In this paper, radioimmunoassay and LOwry method was used to measure the aqueous humor PGE2 and total protein content after corneal penetrating injury in rabbits. Results: After 1, 3, 8, 24, 48, 72 hours after corneal penetrating injury, the content of PGE2 in aqueous humor had a very significant increase compared with the normal value (P <0.01) (P <0.05). TP content in aqueous humor had a very significant increase (P <0.01) 1.3, 8.24.48 hours after injury compared with the normal value, but dropped to 72 hours Normal (P <0.05). We think: PGE2 after corneal penetrating injury. TP content was significantly increased, PGE2 is an important inflammatory mediator of BAB destruction, TP is the result of BAB destruction. They can represent the severity of the inflammatory insult.