研究显示,高血糖患者并发认知功能障碍风险明显增加,而血糖波动较持续高血糖,可能更易引起糖尿病并发症~([1])。1型糖尿病(T1DM)是胰岛B细胞破坏和胰岛素绝对缺乏引起的糖尿病。T1DM患者需长期依赖胰岛素治疗,但由于外源性胰岛素无法模拟内源性分泌,在患者饮食及运动变化时难以维持血糖稳态,极易引起血糖波动~([2])。目前关于血 Studies have shown that patients with hyperglycemia complicated by cognitive impairment significantly increased the risk of blood glucose fluctuations than persistent hyperglycemia may be more likely to cause complications of diabetes ~ ([1]). Type 1 diabetes (T1DM) is diabetes caused by destruction of islet B cells and absolute lack of insulin. Long-term dependence on insulin therapy in patients with T1DM, but exogenous insulin can not simulate the endogenous secretion, in patients with diet and exercise changes is difficult to maintain blood glucose homeostasis, easily lead to fluctuations in blood glucose ~ ([2]). Currently on the blood