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目的:探讨冠心病合并高血压患者冠状动脉病变临床特点。方法:本研究病例来源于2010年4月-2015年11月期间我院心内科收治的冠心病患者340例,按照是否合并高血压分为高血压组(n=148)与非高血压(n=192),行冠状动脉造影检查,比较两组患者临床表现、危险因素及冠状动脉病变造影结果。结果:两组典型胸痛和心源性休克发生率比较无统计学差异(P>0.05);高血压组心律失常、心肌梗死、心力衰竭发生率明显高于非高血压组(P<0.05);两组性别、肥胖病史、吸烟史、血糖水平、TC、TG、HDL-C、LDL-C水平比较无统计学差异(P>0.05);高血压组年龄明显高于非高血压组(P<0.05);高血压组单支血管病变明显少于非高血压(P<0.05)、三支及弥漫病变明显多于非高血压(P<0.05),而两组两支血管病变比较无统计学差异(P>0.05)。结论:冠心病合并高血压患者心律失常、心肌梗死、心力衰竭发生率高,冠状动脉弥漫病变严重,累及左主干较多。
Objective: To investigate the clinical features of coronary artery disease in patients with coronary heart disease complicated with hypertension. Methods: The cases were from 340 patients with coronary heart disease admitted to our hospital from April 2010 to November 2015. According to whether the patients with hypertension were divided into hypertension group (n = 148) and non-hypertension group (n = 192) underwent coronary angiography. The clinical manifestations, risk factors and coronary angiography were compared between the two groups. Results: There was no significant difference between the two groups in the incidence of chest pain and cardiogenic shock (P> 0.05). The incidence of arrhythmia, myocardial infarction and heart failure in hypertension group was significantly higher than that in non - hypertension group (P <0.05). There were no significant differences in gender, obesity history, smoking history, blood glucose level, TC, TG, HDL-C and LDL-C levels between the two groups (P> 0.05). The incidence of single vessel disease in hypertension group was significantly less than that in non-hypertension group (P <0.05), and the three branches and diffuse lesions were significantly more than those in non-hypertension group (P <0.05) Difference (P> 0.05). Conclusion: The incidence of arrhythmia, myocardial infarction and heart failure in patients with coronary heart disease and hypertension is high. The incidence of coronary artery diffuse lesions is serious, involving the left main trunk more.