目的探讨盆腔器官脱垂(POP)患者应用腹腔镜阴道骶骨固定术(LSC)和传统修补术治疗的临床疗效及对其生活质量的影响。方法选取该院2013年1月-2015年5月收治的61例POP患者为研究对象,按手术方式不同分组:29例行LSC为观察组,32例行传统修补术为对照组。记录比较两组术中出血量、手术时间、尿管保留时间及术后卧床时间等手术情况,术前、术后12个月POP定量(POP-Q)分度指示点测量值及女性性功能量表(FSFI)评分,术前、术后6个月、术后12个月盆底功能障碍问卷短表20(PFDI-20)及盆底功能影响问卷简表7(PFIQ-7)评分,术后12个月随访期间并发症与复发情况。结果观察组术中出血量、手术时间、尿管保留时间及术后卧床时间均显著短于对照组,差异有统计学意义(t=19.530、6.138、6.891、7.100,均P<0.01);两组术后12个月Aa点、C点、Ap点、TVL与术前比较,均明显改善,差异均有统计学意义(均P<0.05),且观察组改善幅度更为显著,与对照组比较差异有统计学意义(均P<0.05);与术前比较,两组术后6个月、12个月PFDI-20、PFIQ-7评分均显著改善,差异均有统计学意义(均P<0.01),且观察组改善程度更为显著,与对照组比较差异有统计学意义(均P<0.01);两组术后12个月FSFI评分与术前比较均显著改善,差异均有统计学意义(均P<0.01),且观察组改善程度更为显著,与对照组比较差异有统计学意义(均P<0.01);观察组复发率为0,明显低于对照组的15.63%,差异有统计学意义(χ2=4.240,P<0.05)。结论 POP患者应用LSC治疗创伤性小、术后恢复快,解剖疗效与功能疗效均更佳,生活质量显著提高,复发率低,具有较高临床参考价值。 Objective To investigate the clinical effect of laparoscopic vaginal sacrum fixation (LSC) and traditional repair in patients with pelvic organ prolapse (POP) and its impact on quality of life. Methods Sixty-one patients with POP treated in our hospital from January 2013 to May 2015 were enrolled in this study. The patients were divided into two groups according to the operation method: 29 patients underwent LSC as observation group and 32 patients underwent conventional repair as control group. The operation records of blood loss, operation time, catheter retention time and bed rest time were recorded and compared. The measurement of POP-Q index and the female sexual function before and 12 months after operation were recorded and compared. (PFDI-20) and pelvic floor function questionnaire 7 (PFIQ-7) score before operation, 6 months after operation, 12 months postoperative pelvic floor dysfunction questionnaire, Complications and recurrence during follow-up after 12 months. Results The intraoperative blood loss, operation time, catheter retention time and bed rest time in the observation group were significantly shorter than those in the control group (t = 19.530, 6.138, 6.891, and 7.100, both P <0.01) At 12 months after operation, the Aa point, C point, Ap point and TVL were significantly improved compared with those before operation (all P <0.05), and the improvement in the observation group was more significant. Compared with the control group (P <0.05). Compared with preoperative, the scores of PFDI-20 and PFIQ-7 at 6 months and 12 months after operation in both groups were significantly improved (all P <0.05), the difference was statistically significant <0.01), and the degree of improvement in the observation group was more significant (P <0.01). The FSFI scores at 12 months after operation in both groups were significantly improved, with statistical differences (All P <0.01), and the improvement in the observation group was more significant (P <0.01). The recurrence rate in the observation group was 0, which was significantly lower than that in the control group (15.63% The difference was statistically significant (χ2 = 4.240, P <0.05). Conclusion LS patients treated with traumatic small, rapid recovery after surgery, anatomical and functional efficacy are better, quality of life improved significantly, the recurrence rate is low, with high clinical reference value.