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目的探讨多索茶碱联合细辛脑注射液静脉滴注治疗慢性阻塞性肺疾病(COPD)的临床效果。方法选取慢性阻塞性肺疾病患者150例,采用随机数字表法分为对照组和观察组,分别给予多索茶碱单用和与细辛脑注射液联用治疗;比较两组患者近期疗效、治疗前后肺通气功能指标及住院时间。结果观察组患者近期疗效明显优于对照组,差异有统计学意义(P<0.05);两组患者治疗后肺通气功能指标均优于治疗前,且观察组患者治疗后改善程度高于对照组;同时观察组患者住院时间明显少于对照组,差异均有统计学意义(P<0.05)。结论多索茶碱联合细辛脑注射液静脉滴注治疗COPD可明显改善咳喘症状,提高肺部通气功能,并缩短病程,效果优于多索茶碱单用。
Objective To investigate the clinical effects of doxofylline and asarone injection on chronic obstructive pulmonary disease (COPD). Methods A total of 150 patients with chronic obstructive pulmonary disease (COPD) were selected and divided into control group and observation group by random number table. They were treated with doxofylline alone and combined with Asarone Injection. The short-term curative effect, Ventilatory function and hospital stay before and after treatment. Results The curative effect of observation group was better than that of control group, the difference was statistically significant (P <0.05). Both groups had better pulmonary function after treatment than before treatment, and the improvement in observation group was higher than that of control group ; While the observation group patients hospitalized significantly less than the control group, the difference was statistically significant (P <0.05). Conclusion Doxofylline combined with Asarone Injection intravenous infusion of COPD can significantly improve the symptoms of cough, improve lung ventilation, and shorten the course of the disease, the effect is superior to doxofylline alone.