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目前,临床上对于慢性乙型病毒性肝炎抗病毒治疗的目的是抑制乙肝病毒(HBV)复制、减轻肝组织病变、改善肝功能、降低传染性、减轻或阻止肝纤维化的发生、提高患者的生活质量[1],而在抗病毒治疗的同时,针对肝组织内细胞外基质(ECM)代谢与肝星状细胞(HSC)活化的抗纤维治疗,对于提高患者的生活质量具有重要意义。本文对慢性乙肝患者在予保肝、利胆、抗炎、对症等基础治疗上,应用聚乙二醇
At present, the clinical treatment of chronic hepatitis B virus antiviral therapy is intended to inhibit the replication of hepatitis B virus (HBV), reduce liver disease, improve liver function, reduce infectivity, reduce or prevent the occurrence of liver fibrosis and improve the patient’s Quality of life [1], and anti-viral therapy, in addition to anti-fibrosis treatment of extracellular matrix (ECM) metabolism and hepatic stellate cells (HSC) activation in liver tissue is important for improving the quality of life of patients. In this paper, patients with chronic hepatitis B to liver protection, gallbladder, anti-inflammatory, symptomatic and other basic treatment, the application of polyethylene glycol