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目的探讨动态检测血清癌胚抗原对诊断乳腺癌血行转移的价值。方法观察比较58例已发生血行转移的乳腺癌患者在根治术前、根治术后及发现血行转移时血清癌胚抗原阳性率。结果乳腺癌患者根治手术前和术后1个月血清癌胚抗原阳性率均较低,两者比较差异无显著性(P>0.05);多部位转移者阳性率较单一部位转移者高,但差异无显著性。结论动态观察乳腺癌患者血清癌胚抗原的变化,对监测肿瘤的进展、疗效、转移和复发有一定应用价值。
Objective To investigate the value of dynamic detection of serum carcinoembryonic antigen in the diagnosis of hematogenous metastasis of breast cancer. Methods Fifty-eight patients with breast cancer who had hematogenous metastasis were observed before and after radical surgery and the hematogenous metastasis was found. Results The positive rate of serum carcinoembryonic antigen in patients with breast cancer before operation and one month after operation was lower than that in patients with single site metastasis (P> 0.05). The positive rate of multi-site metastasis was higher than that of single site metastasis No significant difference. Conclusion The dynamic observation of the changes of serum carcinoembryonic antigen in breast cancer patients has certain value in monitoring the progress, efficacy, metastasis and recurrence of tumors.