失血性休克时肠粘膜结构和功能受损是全身炎性反应综合征及休克后多器官衰竭综合征的“始动部位”或“中心器官”,但急救手术过程中使用的麻醉药物对胃肠道的保护作用尚缺乏系统的研究。氯胺酮是失血性休克患者急救手术时常用的麻醉药物,但它对休克再灌注期间肠道灌注及氧合的影响尚无定论。本研究采用失血性休克再灌注动物模 The structure and dysfunction of intestinal mucosa in hemorrhagic shock are the “initiating sites” or “central organs” of the systemic inflammatory response syndrome and post-shock multiple organ failure syndrome, but the anesthetic drugs used in the emergency surgery are not effective on the gastrointestinal Road protection is still lack of systematic research. Ketamine is a commonly used anesthetic for emergency surgery in patients with hemorrhagic shock, but its effect on intestinal perfusion and oxygenation during shock-reperfusion is inconclusive. This study used hemorrhagic shock and reperfusion animal model