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尽管治疗方法不断改进 ,如今对百日咳的控制还主要依赖于菌苗预防〔1〕 ,目前世界各地除日本外均在使用全细胞百日咳菌苗 ,该菌苗能够提供保护水平的免疫力 ,在百日咳的预防方面起到了很大的作用 ,但由于接种后毒性反应较重 ,异常反应的发生率较高 ,特别对极少数儿童可诱发严重
Despite ongoing improvements in treatment, the current control of whooping cough is also largely dependent on vaccine prophylaxis [1]. Currently, whole-cell pertussis vaccines are being used in all parts of the world except Japan, and the vaccine is able to provide a protective level of immunity in whooping cough Of the prevention has played a significant role, but due to severe toxicity after vaccination, the incidence of abnormal response is high, especially for very few children can cause serious