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研究了37例梗阻性黄疸(A组)和90例单纯胆囊结石(D组)T汗淋巴细胞亚群,讨论梗阻性黄疸患者T淋巴细胞变化与胆道压力的关系。A组分为急诊手术(B组)和择期手术(C组)。结果显示A～C组术前CD_8~+、CD_4~+、CD_8~+、CD_4~+/CD_8~+显著低于术后8～12天(P<0.05或P<0.01)。D组术前CD_3~+、CD_4~+、CD_9~+显著低于术后3～7天(P<0.01),术前A组CD_8~+、CD_4~+/CD_8~+显著低于D组(P<0.05),CD_3~+、CD_2~+无显著性差异(P>0.05)。BTP与CD_3~+、CD_8~+、CD_8~+呈负相关(P<0.05,或P<0.01)。因此,作者认为梗阻性黄疽患者T淋巴细胞亚群处于抑制状态。及时解除胆道梗阻是恢复机体T淋巴细胞功能的关键。
Thirty-seven obstructive jaundice (group A) and 90 patients with simple cholecystolithiasis (group D) were used to investigate the relationship between T lymphocyte and biliary tract pressure in patients with obstructive jaundice. Group A consisted of emergency surgery (group B) and elective surgery (group C). The results showed that the preoperative CD_8 ~ +, CD_4 ~ +, CD_8 ~ + and CD_4 ~ + / CD_8 ~ + in group A ~ C were significantly lower than those in group A ~ C 8 ~ 12 days after operation (P <0.05 or P <0.01). The preoperative CD_3 ~ +, CD_4 ~ + and CD_9 ~ + in group D were significantly lower than that in group 3 ~ 7 days after operation (P <0.01). The preoperative CD_8 ~ + and CD_4 ~ + / CD_8 ~ (P <0.05). There was no significant difference between CD_3 ~ + and CD_2 ~ + (P> 0.05). BTP was negatively correlated with CD_3 ~ +, CD_8 ~ + and CD_8 ~ + (P <0.05, P <0.01). Therefore, the author believes that patients with obstructive jaundice in T lymphocyte subsets in the inhibition. The timely release of biliary obstruction is the key to restore the body’s T lymphocyte function.