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用双抗体夹心ELISA法检测49例鼻咽癌患者放疗前后血清可溶性白细胞介素-2受体(sIL-2R)水平。结果显示,鼻咽癌放疗前血清sIL-2R水平不同临床分期及转移性淋巴结大小无显著差异。放疗后血清sIL-2R水平较放疗前显著降低,说明检测血清sIL-2R可作为观察鼻咽癌治疗前后免疫状况的一种方法,是否可以作为衡量近远期疗效的指标有待进一步研究
Serum soluble interleukin-2 receptor (sIL-2R) levels were measured in 49 patients with nasopharyngeal carcinoma before and after radiotherapy with double antibody sandwich ELISA. The results showed that the level of serum sIL-2R in nasopharyngeal carcinoma before radiotherapy with different clinical stages and metastatic lymph node size was no significant difference. Serum sIL-2R level after radiotherapy was significantly lower than before radiotherapy, indicating that serum sIL-2R detection can be used as a way to observe the immune status of nasopharyngeal carcinoma before and after treatment, whether it can be used as a measure of short-term efficacy of the index needs further study