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目的了解浙江省湖州市婚检人群中艾滋病、梅毒和乙型病毒性肝炎(乙肝)的感染情况并作必要性探讨。方法对2008年5月至2010年12月到浙江省湖州市妇幼保健院进行婚前医学检查人群进行乙肝病毒表面抗原(HBsAg)、梅毒抗体及人类免疫缺陷病毒抗体(抗-HIV)检测。结果 21 831名婚检人群中,HBsAg阳性居首位,占4.65%;其次是梅毒抗体阳性,占0.30%;再次是抗-HIV阳性,占0.009%。男、女性HBsAg阳性率差异有统计学意义,男性高于女性(χ2=46.63,P<0.05);男、女性梅毒阳性率差异无统计学意义(χ2=0.38,P>0.05)。2008-2010年HBsAg阳性率有逐渐下降趋势,各年间差异无统计学意义(χ2=3.93,P>0.05);梅毒抗体阳性率有逐渐上升趋势,各年间差异有统计学意义(χ2=10.44,P<0.05);从乙肝三系检测结果看,HBeAg阳性占20.95%,主要为HBsAg+HBeAg+抗-HBc和HBsAg+抗-HBe+抗-HBc两种模式,占83.82%。结论湖州市婚检人群HBsAg、梅毒、HIV感染率不高,但婚检人群作为特殊人群,应引起特别关注;婚前医学检查对疾病控制、普及传染病预防知识、提高生活质量、保障家庭幸福及提高出生人口素质有重要意义。
Objective To understand the prevalence of AIDS, syphilis and hepatitis B in premarital people in Huzhou City of Zhejiang Province and to discuss the necessity. Methods From May 2008 to December 2010, HBsAg, syphilis antibody and human immunodeficiency virus antibody (anti-HIV) were detected in premarital medical examination population in Huzhou MCH Hospital of Zhejiang Province. Results Among the 21 831 premarital people, HBsAg positive was the highest, accounting for 4.65%; followed by syphilis antibody positive, accounting for 0.30%; again, anti-HIV positive, accounting for 0.009%. The positive rate of HBsAg between male and female was statistically significant, and the male was higher than female (χ2 = 46.63, P <0.05). There was no significant difference in the positive rate of syphilis between male and female (χ2 = 0.38, P> 0.05). The positive rate of HBsAg in 2008-2010 showed a gradual downward trend with no significant difference between years (χ2 = 3.93, P> 0.05). The positive rate of syphilis antibody increased gradually (χ2 = 10.44, P <0.05). According to the three-line hepatitis B test results, HBeAg positive accounted for 20.95%, mainly HBsAg + HBeAg + anti-HBc and HBsAg + anti-HBe + anti-HBc two modes, accounting for 83.82%. Conclusions The rate of HBsAg, syphilis and HIV infection in premarital patients in Huzhou City is not high, but the premarital medical examinations should pay special attention as a special population. Premarital medical examination should help to prevent and control infectious diseases, popularize infectious disease prevention knowledge, improve quality of life, protect family happiness and increase birth rate The quality of the population is of great importance.