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目的:探讨临床药师在高位截瘫伴医院获得性肺炎(HAP)患者药物治疗中的作用。方法:临床药师对1例高位截瘫伴HAP患者肺部抗感染治疗无效提出建议,先后给予亚胺培南西司他丁1.0 g,ivgtt,qid,抗感染治疗;头孢哌酮钠舒巴坦钠3.0 g,ivgtt,bid+阿米卡星0.4 g,ivgtt,bid,降阶梯抗感染治疗;氟康唑氯化钠0.2 g,ivgtt,qd,对可能发生的侵袭性真菌感染进行预防性治疗等,协助医师完善药物治疗方案,监测药品不良反应,指导合理用药。结果:采用上述治疗方案3周后,患者症状明显改善。结论:临床药师对患者进行个体化药学监护,减少了治疗过程中应用药物出现的不良反应,提高了药物临床治疗的有效性与安全性。
Objective: To investigate the role of clinical pharmacists in the medication of patients with paraplegia complicated with hospital acquired pneumonia (HAP). Methods: The clinical pharmacist gave advice on the ineffective treatment of pulmonary infection in patients with paraplegia complicated with HAP. The patients were treated with imipenem and cilastatin 1.0 g, ivgtt and qid respectively. Cefoperazone sodium and sulbactam sodium 3.0 g and ivgtt , bid + amikacin 0.4 g, ivgtt, bid, anti-step down anti-infective therapy; fluconazole sodium chloride 0.2 g, ivgtt, qd, the possible occurrence of invasive fungal infections for prophylactic treatment to help physicians improve the drug Treatment programs to monitor drug adverse reactions, to guide the rational use of drugs. Results: After 3 weeks of treatment, the patients’ symptoms improved obviously. Conclusion: The clinical pharmacists conducted personalized pharmacy monitoring on patients, reducing the adverse reactions of the applied drugs in the course of treatment and improving the clinical efficacy and safety of the drugs.