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采用酶联免疫法测定妊娠糖尿病患者与健康妊娠妇女空腹内脂素水平。分析内脂素与各指标之间的关系。结果妊娠糖尿病患者血清内脂素、FPG、FInS、cCP水平明显升高(P<0.05或P<0.01)。血清内脂素水平与FPG、FInS、FCP、HOMA-IR、BMBCI指数呈正相关(P<0.05或P<0.01)。与ISI呈负相关(P<0.01)。结论妊娠糖尿病患者血内脂素水平明显升高,提示内脂素与糖代谢密切相关。内脂素与妊娠糖尿病主要发病机制——胰岛素抵抗之间有关。
The level of fasting visfatin in gestational diabetes mellitus and healthy pregnant women was measured by enzyme-linked immunosorbent assay. Analysis of visfatin and the relationship between the indicators. Results The levels of serum visfatin, FPG, FInS and cCP in gestational diabetes mellitus were significantly increased (P <0.05 or P <0.01). Serum visfatin levels were positively correlated with FPG, FInS, FCP, HOMA-IR and BMBCI (P <0.05 or P <0.01). And ISI was negatively correlated (P <0.01). Conclusion The level of plasma visfatin in gestational diabetes mellitus patients is significantly increased, suggesting that visfatin is closely related to glucose metabolism. Florescein and gestational diabetes the main pathogenesis - insulin resistance between.