采用气相色谱法为定性、定量手段,研究氯霉素在健康鲫鱼肌肉中的残留消除规律。多剂量[40.00 mg/(kg·b·w)]给药后,在鲫鱼肌肉中氯霉素含量随时间的延长而逐渐减少,即1 d为14 281.40μg/kg,2 d为1 426.20μg/kg,4 d为84.00μg/kg,8 d为61.40μg/kg,12 d为32.60μg/kg,16 d为4.50μg/kg,18 d为0.60μg/kg,20 d低于检出限(0.03μg/kg)。以期为氯霉素药物残留的检测提供参考依据。 Gas chromatography was used as a qualitative and quantitative method to study the elimination of chloramphenicol in the muscle of healthy carp. After multiple doses [40.00 mg / (kg · b · w)] administration, the content of chloramphenicol in muscle of the carp decreased gradually with time increasing, that is, 14 281.40 μg / kg for 1 d and 1 426.20 μg for 2 days / kg on day 4, 84.00 μg / kg on day 4, 61.40 μg / kg on day 8, 32.60 μg / kg on day 12, 4.50 μg / kg on day 16 and 0.60 μg / kg on day 18, (0.03 μg / kg). In order to provide a reference for the detection of chloramphenicol drug residues.