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目的探讨比较非酒精性单纯性脂肪肝(NAFL)与非酒精性脂肪性肝炎(NASH)的临床区别,以便于临床诊断与治疗。方法对经肝组织病理检查确诊的非酒精性脂肪肝(NAFLD)80例(单纯性脂肪肝40例,脂肪性肝炎40例)进行B超、肝功能、血脂、血清纤维化指标检测比较。结果 NASH患者在肝功能、血脂、血清纤维化指标上均较NAFL增高,两组比较有统计学差异(P<0.05)。结论非酒精性脂肪肝能转化为脂肪性肝炎甚至肝硬化,尽早的确诊对预后及治疗有着积极的意义。
Objective To investigate the clinical difference between non-alcoholic fatty liver (NAFL) and nonalcoholic steatohepatitis (NASH) for clinical diagnosis and treatment. Methods 80 cases of non-alcoholic fatty liver (NAFLD) diagnosed by liver histopathology (40 cases of simple fatty liver and 40 cases of steatohepatitis) were examined by B-ultrasound, liver function, blood lipid and serum fibrosis. Results The liver function, blood lipid and serum fibrosis indexes of NASH patients were higher than those of NAFL patients. There was significant difference between the two groups (P <0.05). Conclusion Non-alcoholic fatty liver can be transformed into steatohepatitis or even cirrhosis, and early diagnosis is of great significance to prognosis and treatment.