子痫前期(preeclampsia,PE)是一种妊娠期危及母儿安全的严重并发症,也是妊娠期母儿发病和死亡的重要原因,常累及心、脑、肝、肾和胎盘等重要器官,发生多器官功能障碍,表现为高血压、水肿、蛋白尿、凝血机制障碍、头痛、胎儿生长受限等。近年来,人们对PE的发病机制进行了大量的研究,但其具体病因仍不十分明确。及时准确的诊断和治疗,适时终止妊娠,积极器官支持,有效的改善母儿预后显得尤为重要。 Preeclampsia (PE) is a serious complication that threatens the safety of pregnant women during pregnancy. It is also an important cause of maternal and fetal morbidity and mortality in pregnancy. It often affects vital organs such as heart, brain, liver, kidneys and placenta. Multiple organ dysfunction, manifested as hypertension, edema, proteinuria, coagulation disorders, headache, fetal growth restriction and so on. In recent years, a great deal of research has been done on the pathogenesis of PE, but its exact cause is still not very clear. Timely and accurate diagnosis and treatment, timely termination of pregnancy, active organ support, effective in improving the prognosis of maternal and child is particularly important.