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目的 分析合并2型糖尿病的乳腺癌患者临床病理特征及预后效果?方法 病例收集时间为2019年1月至2020年7月，选择来我院就诊的120例原发性乳腺癌患者为观察对象，其中将合并2 型糖尿病的乳腺癌患者(50例)设为观察组，将非糖尿病的乳腺癌患者 (70例)设为对照组，对比两组患者的临床病理学特征以及预后效果?结果 两组患者的临床一般资料对比，观察组患者的年龄?绝经后患者比例以及体质量指数(BMI)均明显高于对照组，差异有统计学意义(P<0.05);观察组患者的乳腺肿瘤直径大于对照组，两组肿瘤分期?腋窝淋巴结“,”Objective To analyze and evaluate the clinicopathological features and prognosis of breast cancer patients with type 2 diabetes mellitus.Methods The cases were collected from January 2019 to July 2020，120 patients with primary breast cancer were selected as the observation subjects.Among them，2 patients with type 2 diabetes mellitus (50 cases) were selected as the observation group.The patients with non-diabetic breast cancer (70 cases) were allocated as the control group.The clinicopathological characteristics and prognosis of the two groups were compared and analyzed.Results The age，proportion of postmenopausal patients and body mass index (BMI) in the observation group were significantly higher than those in the control group (P<0.05).The diameter of breast tumor in the observation group was larger than that in the control group.There were signi?cant differences in tumor stage，positive rate of axillary lymph nodes，negative rate of estrogen receptor (ER)，blood glucose，blood lipid，C-reactive protein (CRP)，serum cystatin C (Cys-C) between the two groups (P<0.05).The recurrence and metastasis probability and complication rate in the observation group were higher than those in the control group (P<0.05).The length of hospital stay，out of bed activity time and drainage volume were more than those in the control group (P<0.05).Conclusion Diabetes is a high risk factor for breast cancer.Its prognosis is poor，its pathological stage is late，its blood sugar level is high，its metastasis risk is high，and its survival rate is low.Therefore，individualized treatment should be given to patients，and postoperative follow-up and regular review should be emphasized.