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目的:探讨亚临床甲减血脂、血糖、血尿酸变化及意义。方法:测定80例亚临床甲减患者血糖(GLU)、总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、血尿酸(UA)水平,设健康对照组78例进行比较。结果:亚临床甲减组TSH、TC、TG、LDL-C、UA明显升高,而HDL-C明显下降,有统计学差异(P<0.05)。血糖水平虽有下降,但无统计学差异。结论:亚临床甲减脂代谢紊乱和高尿酸血症可能是促进动脉粥样硬化重要的危险因素。
Objective: To explore the clinical significance of subclinical hypothyroidism, blood glucose and serum uric acid. Methods: The blood glucose, total cholesterol, triglyceride, LDL-C, HDL-C, Serum uric acid (UA) levels, a healthy control group of 78 patients were compared. Results: The levels of TSH, TC, TG, LDL-C and UA in subclinical hypothyroidism were significantly increased, while HDL-C was significantly decreased (P <0.05). Although blood glucose levels declined, but no statistical difference. Conclusion: Metabolic disturbance of hypothyroidism and hyperuricemia in subclinical hypothyroidism may be important risk factors for promoting atherosclerosis.