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目的：研究替硝唑漱口水的稳定性。方法：用ＨＰＬＣ测定替硝唑的含量，恒温加速试验预测替硝唑漱口水的有效期。结果：替硝唑分解属一级动力学过程，ｔ２５℃０．９为６．１年。结论：确定替硝唑漱口水的有效期定为２年以上。
Objective: To study the stability of tinidazole mouthwash. Methods: The content of tinidazole was determined by HPLC. The isothermal accelerated test was used to predict the effective period of tinidazole mouthwash. Results: Tinidazole decomposition is a first-order kinetic process, t25 ℃ 0.9 for 6.1 years. Conclusion: Tinidazole mouthwash is validated for more than 2 years.