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目的:观察自拟中药汤剂联合西医常规治疗重症急性胰腺炎的临床疗效。方法:将66例重症胰腺炎患者随机分为两组,对照组33例采用常规西医对症治疗;治疗组33例在西医常规治疗基础上按病情分为初期、进展期、恢复期分别给予自拟中药汤剂随证治疗,两组均为14天为1个疗程,1个疗程后观察两组患者在第1、3、7、14天的急性生理与慢性健康评分(APACHE-Ⅱ)评分变化及总显效率。结果:两组在第1、14天的急性生理与慢性健康评分(APACHE-Ⅱ)无统计学差异(P>0.05),在第3、7天有统计学差异(P<0.05);治疗组痊愈22例,有效10例,无效1例,总有效率为96.97%;对照组痊愈10例,有效4例,无效19例,总有效率为42.42%,治疗组疗效优于对照组(P<0.05)。结论:分期自拟中药汤药联合西医常规治疗重症急性胰腺炎患者临床疗效满意,值得推广。
Objective: To observe the clinical curative effect of self-made traditional Chinese medicine decoction combined with western medicine in the treatment of severe acute pancreatitis. Methods: Sixty-six patients with severe acute pancreatitis were randomly divided into two groups. The control group received routine western medicine symptomatic treatment. The treatment group was divided into initial stage, advanced stage and convalescent stage on the basis of conventional treatment Chinese medicine decoction with card treatment, both groups were 14 days for a course of treatment, after a course of treatment were observed in two groups of patients on the 1st, 3rd, 7th and 14th days of acute physiology and chronic health score (APACHE-Ⅱ) score changes And total significant efficiency. Results: There was no significant difference in acute physiology and chronic health score (APACHE-Ⅱ) between the two groups on the first and the 14th day (P> 0.05), and on the 3rd and 7th day (P <0.05) In the control group, 10 cases were cured, 4 cases were effective, 19 cases were ineffective, and the total effective rate was 42.42%. The curative effect of the treatment group was better than that of the control group (P < 0.05). Conclusion: The clinical efficacy of staged self-made traditional Chinese medicine and traditional Chinese medicine combined with Western medicine in the treatment of severe acute pancreatitis is satisfactory and worthy of promotion.