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有关抑癌基因 p1 6蛋白在卵巢癌中表达已有报道 ,但 p1 6基因异常与蛋白表达关系尚有争议 ,未见到有关应用 m RNA原位杂交技术检测卵巢浆液性肿瘤 p1 6m RNA表达研究的报道。本研究应用原位杂交技术对 55份手术切除的冰冻新鲜标本进行p1 6m RNA检测 ,以探讨 p1 6m RNA表达与卵
The expression of the tumor suppressor gene p16 in ovarian cancer has been reported, but there is controversy about the relationship between the abnormality of p16 gene and the protein expression. The study on the expression of p16mRNA in ovarian serous tumors by m RNA in situ hybridization has not been reported Report. In this study, 55 fresh frozen surgically resected p1 6m RNA samples were detected by in situ hybridization to explore the relationship between p1 6m RNA expression and egg