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目的探讨重组人干扰素α2a栓联合微波治疗慢性宫颈炎患者的临床疗效。方法选取2008年3月至2011年3月扬中市计划生育指导站门诊收治的160例慢性宫颈炎患者作为研究对象,按随机数字表法将其分为观察组与对照组,各80例。对照组患者采用阿奇霉素联合克拉霉素进行治疗,观察组采用重组人干扰素α2a栓联合微波治疗,比较两组患者的临床疗效、疾病复发情况及不良反应发生情况。结果观察组患者治疗的总有效率明显高于对照组,差异有统计学意义(P<0.05);观察组患者慢性宫颈炎复发率明显低于对照组,差异有统计学意义(P<0.05)。两组患者不良反应比较差异无统计学意义(P>0.05)。结论微波辐射治疗慢性宫颈炎后给予重组人干扰素α2a栓进行抗感染,临床效果明显,可有效降低复发率,安全可靠。
Objective To investigate the clinical efficacy of recombinant interferon α2a combined with microwave in the treatment of patients with chronic cervicitis. Methods A total of 160 patients with chronic cervicitis treated at the outpatient department of Yangzhong Family Planning Guide Station from March 2008 to March 2011 were selected as study subjects and divided into observation group and control group according to random number table method, each of 80 cases. Patients in the control group were treated with azithromycin combined with clarithromycin. The observation group was treated with recombinant interferon α2a combined with microwave. The clinical efficacy, recurrence and adverse reactions of the two groups were compared. Results The total effective rate of observation group was significantly higher than that of control group (P <0.05). The recurrence rate of chronic cervicitis in observation group was significantly lower than that of control group (P <0.05) . There was no significant difference in adverse reactions between the two groups (P> 0.05). Conclusion Microwave radiation treatment of chronic cervicitis given recombinant human interferon α2a suppositories for anti-infection, the clinical effect is obvious, can effectively reduce the recurrence rate, safe and reliable.