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1965年应用小鼠腹水型网状细胞肉瘤(代号ARS)制备成无细胞提取液,皮下注射于昆明种新生乳鼠,建成一株可连续传递的白血病瘤株(代号L6565),迄今已传95代。病鼠的平均潜伏期为60～65天,全身淋巴结、脾脏和胸腺皆明显肿
In 1965, mouse ascites reticular cell sarcoma (ARS) was used to prepare a cell-free extract, subcutaneously injected into Kunming neonatal mice, and a continuous leukemia cell line (code name L6565) was established. generation. The average latency of diseased mice is 60-65 days, and the whole body lymph nodes, spleen and thymus are significantly swollen