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目的 研究脑梗死患者颈动脉粥样硬化的程度,分析低密度脂蛋白(LDL)、氧化低密度脂蛋白(OX-LDL)与颈动脉粥样硬化的关系。方法 B超测定脑梗死组及对照组的颈动脉内膜-中膜厚度(intimalmedia thickness;IMT)。测定受试者的LDL、OX-LDL。比较各脑梗死组及对照组的IMT和LDL、OX-LDL。对IMT和LDL、OX-LDL相关分析。结果 伴糖尿病的脑梗死组IMT高于其它脑梗死组及对照组。IMT与LDL、OX-LDL显著正相关。结论 脑梗死患者的颈动脉粥样硬化程度显著高于对照组; 其中伴有糖尿病的脑梗死患者的颈动脉粥样硬化程度尤为明显, LDL、OX-LDL是促进颈动脉粥样硬化的关键因子。
Objective To study the degree of carotid atherosclerosis in patients with cerebral infarction and to analyze the relationship between low density lipoprotein (LDL), oxidized low density lipoprotein (OX-LDL) and carotid atherosclerosis. Methods B ultrasound was used to measure carotid artery intima - media thickness (IMT) in cerebral infarction group and control group. Subjects were tested for LDL, OX-LDL. The IMT and LDL, OX-LDL in each cerebral infarction group and control group were compared. For IMT and LDL, OX-LDL correlation analysis. Results IMT in diabetic cerebral infarction group was higher than those in other cerebral infarction group and control group. IMT and LDL, OX-LDL significant positive correlation. Conclusions The degree of carotid atherosclerosis in patients with cerebral infarction is significantly higher than that in the control group. The degree of carotid atherosclerosis in patients with diabetes mellitus is particularly obvious. LDL and OX-LDL are the key factors to promote carotid atherosclerosis .