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报告采用直流电锌离子导入治疗伴有血清锌水平降低或血清铜/锌比值异常的26例视网膜色素变性病人的初步疗效。病人经20～30次的治疗后,视力提高三行以上的眼数有15.38%;视野改善超过5°的眼数为4%,暗适应阈值下降幅度大于1.0的眼数为13.46%,其余为视功能无改变或变化不大者。治疗前后病人的眼底形态没有明显变化;4例8眼的治疗前后 ERG 检查结果基本一致。文章还就锌离子导入法和口服锌化合物制剂法的优缺点比较,直流电对视力的可能增强作用,锌元素与维生素 A 代谢的关系及影响暗适应的机制,作了简要的讨论。
The report reported the initial efficacy of direct current zinc iontreatment in 26 patients with retinitis pigmentosa associated with decreased serum zinc levels or abnormal serum copper / zinc ratio. After 20 to 30 times of treatment, the number of eyes with vision improvement of more than three rows was 15.38%; the number of eyes with vision improvement of more than 5 ° was 4%; the number of eyes with dark adaptation threshold reduction of more than 1.0 was 13.46%; the others were No change in visual function or little change. Before and after treatment, there was no significant change in the shape of fundus. The results of ERG in 4 cases and 8 eyes before and after treatment were basically the same. The article also briefly discussed the advantages and disadvantages of zinc ion introduction method and oral zinc compound preparation method, the potential enhancement of direct current to visual acuity, the relationship between zinc and vitamin A metabolism and the mechanism of dark adaptation.