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急性冠脉综合征(ACS)是一种常见的心血管疾病,近年来发病率呈逐年上升趋势,严重危害居民健康[1]。凝集素样氧化低密度脂蛋白受体-1(LOX-1)是连接氧化应激和炎症反应的纽带,与ACS疾病发生及进展密切相关[2-3]。有研究发现,LOX-1可被某些蛋白水解酶及炎性因子裂解为可溶性凝集素样氧化低密度脂蛋白受体-1(s LOX-1)并释放入血,可作为早期诊断急性心肌梗死的一个指标,有重要的
Acute coronary syndrome (ACS) is a common cardiovascular disease, the incidence in recent years showed an upward trend year by year, seriously endangering the health of residents [1]. Lectin-like Oxidized Low Density Lipoprotein Receptor-1 (LOX-1), a link between oxidative stress and inflammatory response, is closely related to the occurrence and progression of ACS [2-3]. Some studies have found that LOX-1 can be cleaved by some proteolytic enzymes and inflammatory factors into soluble lectin-like oxidized low density lipoprotein receptor-1 (sLOX-1) and released into the blood, which can be used as an early diagnosis of acute myocardial infarction An indicator of infarction is important