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环氧化酶(cyclooxygenase,COX)是花生四烯酸转化为前列腺素类物质过程中的重要限速酶,其产物在许多生理和病理过程中发挥作用。目前已知的COX有COX-1和COX-2两种。COX-1为结构性表达,几乎存在于机体所有组织中,参与维持机体正常的生理活动,炎症等刺激下表达仅上升2～4倍;COX-2
Cyclooxygenase (COX) is an important rate-limiting enzyme in the conversion of arachidonic acid to prostaglandins, and its products play a role in many physiological and pathological processes. Currently known COX COX-1 and COX-2 two. COX-1 is constitutively expressed and exists in almost all tissues of the body and is involved in maintaining the normal physiological activity of the body. The expression of COX-2 is only increased by 2 to 4 times. COX-2