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宫颈癌浸润转移是患者死亡的主要原因,也是决定临床治疗和评估预后的重要指标。有关其分子机制的研究表明,这是一个多阶段复杂的过程,其中包括黏附、运动、酶解及血管新生等,每一阶段都受着不同因素的影响及相关基因的调控。如黏附分子CD44v6、整合素、基质金属蛋白酶等。介绍近年来有关转移相关分子在宫颈癌浸润转移研究领域的新进展。
Invasion and metastasis of cervical cancer is the main cause of death in patients, but also determine the clinical treatment and prognosis of an important indicator. Studies on its molecular mechanisms have shown that this is a multi-stage complex process involving adhesion, exercise, enzymatic hydrolysis and angiogenesis, each of which is influenced by different factors and regulated by related genes. Such as adhesion molecules CD44v6, integrins, matrix metalloproteinases. The recent advances in the field of metastasis-related molecules in metastasis of cervical cancer are introduced.