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目的:研究血清降钙素原(PCT)在社区获得性肺炎(CAP)病原学检测及治疗中的临床意义。方法:我院确诊CAP的病人共157例,所有病人入组时全部进行PCT检测以及细菌培养,分析血清PCT与细菌培养结果及与重症肺炎的关系。结果:PCT>0.5 ng/ml组细菌培养阳性率明显高于PCT<0.5 ng/ml组(67.4%&29.2%,P<0.05);重症肺炎组PCT值明显高于非重症肺炎组(2.2±0.6 ng/ml&0.78±0.2 ng/ml,P<0.05);重症肺炎组细菌培养阳性率明显高于非重症肺炎组(76.1%&41.4%,P<0.05)。结论:血清PCT水平有助于判断CAP的感染性质和指导抗生素的治疗,有利于评估病情的严重程度及预测预后。
Objective: To investigate the clinical significance of serum procalcitonin (PCT) in the detection and treatment of community-acquired pneumonia (CAP) etiology. Methods: A total of 157 CAP patients were diagnosed in our hospital. All patients were enrolled in the PCT test and bacterial culture. The relationship between serum PCT, bacterial culture and severe pneumonia was analyzed. Results: The positive rate of bacterial culture in PCT> 0.5 ng / ml group was significantly higher than that in PCT <0.5 ng / ml group (67.4% vs 29.2%, P <0.05). The PCT value in severe pneumonia group was significantly higher than that in non-severe pneumonia group ± 0.6 ng / ml and 0.78 ± 0.2 ng / ml, P <0.05). The positive rate of bacterial culture in severe pneumonia group was significantly higher than that in non-severe pneumonia group (76.1% vs 41.4%, P <0.05). Conclusion: The level of serum PCT can help determine the nature of CAP infection and guide the treatment of antibiotics, which can help assess the severity of the disease and predict the prognosis.