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Caveolin-3是细胞膜穴样凹陷膜结构域的主要结构蛋白。动物研究显示caveolin-3可在心肌细胞和骨骼肌细胞表达,但在其他细胞不表达。最近研究发现caveolin-3基因的异常与某些类型肌营养不良密切相关,而在caveolin-3转基因或敲除鼠中可见骨骼肌异常。这些结果表明caveolin-3在骨?
Caveolin-3 is the major structural protein in caveolae membrane domains. Animal studies have shown that caveolin-3 is expressed in cardiomyocytes and skeletal muscle cells but not in other cells. Recent studies have found that caveolin-3 gene abnormalities are closely related to some types of muscular dystrophy, whereas skeletal muscle abnormalities can be seen in caveolin-3 transgenic or knockout mice. These results show that caveolin-3 in bone?