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1975年东京报道7例无症状携带母婴传播HBV感染。台湾报道在158例母亲携带者中发生6例婴儿感染。后来关于HBV携带者母亲在围产期传播给其婴儿的报道很多。结果说明HBV携带状态可能是PHC的一个重要的病原学因素。这种传染的危险各国不尽相同。一般地说,在携带率高的国家,特别是亚洲国家或亚洲籍人群,婴儿感染要高于低携带率的国家,特别是北美及西欧的高加索人,家庭中或社会上的HBV携带者可使婴儿出生后即被感染(产后传播),这可能是在中发地
Seven cases of asymptomatic mother-to-child transmission of HBV infection were reported in Tokyo in 1975. Taiwan reported 6 infantile infections in 158 mothers. Later on, many mothers of HBV carriers were reported to their infants during the perinatal period. The results suggest that HBV status may be an important etiological factor of PHC. The dangers of such infections vary from country to country. In general, infant carriers are more likely to be infected in countries with higher rates of delivery, especially those in Asia or Asian populations, than in countries with low rates of carriage, particularly Caucasians in North America and Western Europe, and those with HBV at home or in society The baby is infected after birth (postpartum transmission), which may be in the hair