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目的:观察丹参注射液辅助治疗小儿支气管肺炎临床疗效和安全性。方法:选取收治的70例小儿支气管肺炎患儿,随机分为观察组和对照组各35例。对照组采用常规治疗方案,观察组在对照组治疗的基础上,加用丹参注射液。治疗5~7天后,对比两组患儿的临床疗效以及不良反应。结果:治疗5~7天后,观察组的患儿中,治愈18例,总有效率为97.14%,明显高于对照组治愈10例及总有效率85.71%,差异具有统计学意义(P<0.05)。观察组患儿咳嗽停止的平均时间为(4.58±0.62)天,气促消失的平均时间为(3.59±1.18)天,肺部罗音消失的平均时间为(5.84±0.81)天,平均住院天数为(7.34±0.57)天,以上数据均明显少于对照组患儿,差异均有统计学意义(P<0.05)。两组患儿体温恢复时间比较,差异无统计学意义(P>0.05)。两组患儿治疗过程中均未出现严重不良反应。结论:运用丹参注射液辅助治疗小儿支气管肺炎,能够明显提高临床疗效,缩短患儿的住院天数,有效改善患儿临床症状,且安全性高。
Objective: To observe the clinical efficacy and safety of Danshen injection in the treatment of bronchial pneumonia in children. Methods: Seventy children with bronchopneumonia were selected and randomly divided into observation group and control group with 35 cases each. The control group with conventional treatment programs, the observation group in the control group based on the treatment, plus Salvia injection. After 5 to 7 days of treatment, the clinical efficacy and adverse reactions of the two groups were compared. Results: After treatment for 5-7 days, 18 cases were cured and the total effective rate was 97.14% in the observation group, which was significantly higher than that in the control group (10 cases, 85.71%), the difference was statistically significant (P <0.05 ). The average time for stopping cough in observation group was (4.58 ± 0.62) days, the average time for disappearance of shortness of breath was (3.59 ± 1.18) days, the average time for pulmonary rales disappearing was (5.84 ± 0.81) days, the average length of stay (7.34 ± 0.57) days, the above data were significantly less than the control group, the difference was statistically significant (P <0.05). There was no significant difference in body temperature recovery time between the two groups (P> 0.05). Two groups of children with no serious adverse reactions during treatment. Conclusion: The adjuvant treatment of infantile bronchopneumonia with Salvia miltiorrhiza injection can significantly improve the clinical curative effect, shorten the hospitalization days, effectively improve the clinical symptoms of children and have high safety.