作者报告一个家庭中2名弟兄及其舅(均为儿童)先后患暴发性传染性单核细胞增多症,其中1名(弟弟6岁)病死,另2名发生获得性丙种球蛋白缺乏症。例1发病年龄为5个月,临床表现为高热、颈淋巴结肿大、肝脾肿大、胸腔积液、腹水及脑膜脑炎,血清嗜异性抗体阳性,病中及恢复期EBV抗体1:10。白细胞12,000,淋巴细胞90％,其中大多数为异型细 The author reported that two brothers and their uncles (both children) in a family were suffering from fulminant infectious mononucleosis. One (younger brother 6 years old) died and the other two acquired acquired gamma globulin deficiency. Case 1 The age of onset was 5 months. The clinical manifestations were high fever, cervical lymph node enlargement, hepatosplenomegaly, pleural effusion, ascites and meningoencephalitis, serum HBsAg positive, EBV antibody 1:10 . 12,000 leukocytes, 90% of lymphocytes, most of which are allomorphic