氨曲南(Aitreonam)为第一个在临床应用的单环β内酰胺类抗生素。本品不被葡萄球菌产生的β内酰胺酶水解,比先锋霉素还稳定。其作用机理同青霉素—抑制细菌细胞壁的合成从而杀灭细菌。氨曲南对产酶或不产酶的脑膜炎奈瑟氏菌及淋球菌有效,对抗氨苄青霉素、氯霉素,复方新诺明的流感嗜血杆菌有效,对大多数革蓝氏阴性杆菌及大多数肠杆菌、绿脓杆菌、大肠杆菌、肺炎克雷白氏菌、普通及奇异变 Aitreonam is the first monocyclic beta-lactam antibiotic to be used clinically. This product is not Staphylococcus aureus β-lactamase hydrolysis, more stable than the cephalosporin. Its mechanism of action with penicillin - inhibition of bacterial cell wall synthesis to kill bacteria. Aztreonam on enzyme-producing or non-enzyme-producing Neisseria meningitidis and Neisseria gonorrhoeae effective against ampicillin, chloramphenicol, cotrimoxazole Haemophilus influenzae effective for most of the gram-negative bacilli and Most Enterobacteriaceae, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, common and singularly variable