耳蜗性聋动物模型复制是研究耳蜗植入对语前登与语言期聋患儿影响的关键性实验技术。以往动物模型多采用全身或中耳注射耳毒性药物造模，致使动物全身性或耳蜗以外结构如有前庭系统同时受损，干扰了实验结果的科学性。该文报告经圆窗膜新霉素一次性耳蜗内注入诱发耳蜗性聋的新 Cochlear deaf animal model replication is a key experimental technique to study the effect of cochlear implants on prelingual and speech-deaf children. In the past, animal models were mostly made of whole body or middle ear with ototoxic drugs, which led to the disturbance of the scientific results of the experimental results if the animal body or other structures outside the cochlea were impaired at the same time. This article reports a new cochlear deafness induced by intracisternal injection of neomycin in the round window