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目的:评价白蛋白与呋塞米联用对肝硬化腹水患者伴自发性腹膜炎的临床疗效。方法:选取2012年1月—2014年1月间收治的肝硬化腹水伴自发性腹膜炎患者62例,根据不同的治疗方法将其分为观察组(32例)和对照组(30例);对照组患者均给予常规内科治疗,观察组患者在对照组治疗的基础上加用白蛋白与呋塞米联用治疗,比较两组患者治疗后的临床疗效。结果:治疗后观察组患者临床的总有效率为96.88%,明显高于对照组为73.33%(P<0.05);血清丙氨酸转氨酶(ALT)、总胆红素(TBIL)和血清白蛋白(ALB)值明显优于对照组(P<0.05);腹胀缓解时间、腹水消退时间明显短于对照组(P<0.05);血电解质浓度(K~+、Na~+、Cl~-)值明显低于对照组(P<0.05)。结论:白蛋白与呋塞米联用对肝硬化腹水伴自发性腹膜炎患者的临床疗效较满意,可显著改善患者的肝功能,其腹水消退时间明显缩短。
Objective: To evaluate the clinical efficacy of albumin and furosemide combined with spontaneous peritonitis in cirrhotic patients with ascites. Methods: Sixty-two patients with cirrhosis and spontaneous peritonitis who were admitted to our hospital from January 2012 to January 2014 were divided into observation group (32 cases) and control group (30 cases) according to different treatment methods. Control The patients in the two groups were given conventional medical treatment. The patients in the observation group were treated with albumin and furosemide on the basis of the control group, and the clinical efficacy was compared between the two groups after treatment. Results: After treatment, the total effective rate of clinical observation group was 96.88%, which was significantly higher than that of control group (73.33%, P <0.05). Serum alanine aminotransferase (ALT), total bilirubin (TBIL) and serum albumin (ALB) was significantly higher than that of the control group (P <0.05). The time of abdominal distension and ascites extinction was significantly shorter than that of the control group (P <0.05). The levels of K +, Na + and Cl ~ Significantly lower than the control group (P <0.05). Conclusion: The combination of albumin and furosemide in patients with cirrhosis and spontaneous peritonitis is more satisfied with the clinical efficacy, can significantly improve the patient’s liver function, ascites regression time was significantly shorter.