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目的探索新药设计创新理论.方法研习自然法则,归纳、整理、桥接、整合传统药与现代药物设计之间的关系.结果结合科学天然药发展,创造性地提出科学天然药之药物设计——基于传统医药的启示和指引,结合现代药物设计的理论和成果,创造性地设计新结构,主要应用孪药设计、前药设计、软药设计等理论.结果科学天然药之药物设计可能是一条多快好省的创新药物设计之路,可以实现1+1+???> n 的结果.“,”PURPOSE To explore the innovation theory of drug design. METHOD According to the study of the laws of nature, finding the relationship between the traditional medicine and modern drug design. RESULT Combined with the development of the science of natural medicine, creatively put forward the natural medicine drug design scientificaly - based on the inspiration and guidance of traditional Chinese medicine, combined with the theory of modern drug design and achievement, creatively design of the new structure, the main application includes twin drug design, prodrug design, soft drug design and so on. RESULT Scientificaly drug design of natural medicine may be a better way for drug design, we can achieve the result of 1+1+…>n