利西那肽是一种皮下注射使用的胰高血糖素样肽-1(Glucagon-like peptide-1,GLP-1)受体激动剂,主要用于经饮食和锻炼控制不佳的成人2型糖尿病的辅助治疗。本品最常见的不良反应为恶心、呕吐、头痛、腹泻、晕眩等。本文通过对利西那肽进行文献检索,对其药理作用、药动学、临床评价、安全性、用法用量和药物相互作用进行综述。 Lixinsetin is a subcutaneously administered Glucagon-like peptide-1 (GLP-1) receptor agonist, mainly used in adults with poorly controlled diet and exercise Diabetes adjuvant therapy. The most common adverse reactions of this product are nausea, vomiting, headache, diarrhea, dizziness and so on. In this paper, we reviewed the pharmacological effects, pharmacokinetics, clinical evaluation, safety, usage dosage and drug interactions of licina peptide through literature search.