本研究成功地采用羧甲基纤维素钠(NaCMC)制成抗人体丝虫病药枸橼酸乙胺嗪(DECC)缓释片。对羧甲基纤维素钠的2%(W/V)水分散液,于25℃时进行标化,当流动指数为0.6551时,用Haake Rotovisko粘度计测碍NaCMC 粘度应为18.66泊。用重压法将NaCMC 制成颗粒(<40>60目,BS),真空干燥。将干颗粒按不同比例与52 mg DECC 混合均匀,用单冲压片机,冲头为9.3 mm 直接压成片剂。用 In this study, sodium carboxymethylcellulose (NaCMC) was successfully used to prepare DECC sustained-release tablets against human filariasis. The 2% (w / v) aqueous dispersion of sodium carboxymethylcellulose is normalized at 25 ° C. When the flow index is 0.6551, the viscosity of the NaCMC as determined by a Haake Rotovisko viscometer should be 18.66 poise. NaCMC was pelleted (<40> 60 mesh, BS) by heavy pressing and dried under vacuum. The dry granules were mixed with 52 mg of DECC in varying proportions and pressed directly into tablets using a single punch tablet press with a punch of 9.3 mm. use