论文部分内容阅读
目的 为临床安全用药提供实验依据。方法 小鼠、大鼠的急性及慢性毒性试验。结果 小鼠口服最大耐受量 (MTD)达 16g/kg ,为成人临床用量的 160倍 ;大鼠慢性毒性试验未见毒性反应。 结论 归蓉补血片临床剂量口服安全。
Objective To provide experimental basis for clinical safe drug use. Methods Acute and chronic toxicity tests in mice and rats. Results The oral tolerated dose (MTD) of mice reached 16g/kg, which was 160 times of the clinical dosage in adults. No toxic reaction was found in chronic toxicity test in rats. Conclusion The clinical dose of Guirong Buxue tablet is safe.