安乃近片具较显著的解热镇痛和消炎抗风湿作用,起效快而强,临床应用较多.药典法用滴定法测定其含量,但终点不敏锐,本文采用HPLC,以0.005mol/L氢氧化四丁基胺(用水将13.2ml 10%氢氧化四丁基胺溶液稀释到900ml,用1mol/L的磷酸调pH至5.0,然后用水稀释至1000ml,摇匀)-乙腈(80:20)为流动相,外标法测定方法简便、快速,结果较为满意. Analgetic tablets with more significant antipyretic analgesic and anti-inflammatory anti-rheumatic effect, rapid and strong onset, clinical application more.Pharmacodometry with titration method for the determination of its content, but the endpoint is not sensitive, this article HPLC, 0.005mol / L tetrabutylammonium hydroxide (13.2ml 10% solution of tetrabutylammonium hydroxide diluted to 900ml with water, adjust pH to 5.0 with 1mol / L phosphoric acid and dilute to 1000ml with water, shake) -acetonitrile (80 : 20) as the mobile phase, the external standard method is simple and rapid, the results are more satisfactory.