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对于胆固醇结石(CS)形成机制的研究已有近一百年的历史.开始很长一段时间一直处于假说的水平.本世纪60年代Small等人提出了胆汁胆固醇过饱和理论并得到了广泛的接受.但近3～7年的研究又有了很多新的发现,已使我们对CS形成机制的概念在Small理论基础上有了很大的转变.“Small三角”理论及其缺陷
The study of the mechanism of cholesterol formation has been nearly a hundred years old and has been at the level of the hypothesis for a long time. Small et al. Proposed the theory of bile-cholesterol supersaturation in the 1960s and was widely accepted But there are a lot of new discoveries in the recent 3 ~ 7 years of research, which have greatly changed the concept of CS formation mechanism on the basis of Small Theory. “Small triangle theory” and its defects