恶性肿瘤的最基本特征是肿瘤细胞的失控性增殖,而细胞失控性增殖的根本原因就是细胞调控机制的破坏。细胞调控机制的破坏会造成基因组不稳定性,从而使肿瘤细胞不仅恶性增殖,还发生一系列恶性表型的改变。因此,细胞的调控成为当前肿瘤研究的热点。肿瘤细胞内离子通道的正常表达有助 The most basic feature of malignant tumors is the uncontrolled proliferation of tumor cells, and the fundamental reason for the uncontrolled proliferation of cells is the destruction of cell regulatory mechanisms. The destruction of cell regulatory mechanism will cause genomic instability, so that tumor cells not only malignant proliferation, but also a series of malignant phenotype changes. Therefore, the regulation of cells has become the current focus of cancer research. The normal expression of ion channels in tumor cells is helpful