Trichosanthin is a type I ribosome inactivating protein,with a variety of medical functionincluding anti-virus. The primary and three-dimensional structure of trichosanthin were reported previously,which contained 234 amino acid residues. In this communication we present the resultsabout the revision of the three-dimensional structure based on a solvent flattened map accor-ding to the primary structure revised by Collins et al. and checked by a Chinese group,Which will be described in detail elsewhere.