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目的:观察阿达帕林凝胶外用、中药泡洗联合阿维A胶囊治疗多发性跖疣的临床疗效和安全性。方法:将64例多发性跖疣患者按照就诊先后顺序随机分成两组,对照组32例,给予阿达帕林凝胶外用、中药泡洗疗法治疗;治疗组32例,在对照组基础上加用阿维A胶囊。在治疗第1个月和第2个月时各观察1次且同时记录患部皮疹情况。记录治疗组治疗结束时的肝、肾功能及血脂情况。比较两组最终临床疗效。结果:治疗1个月后,对照组总显效率为25.0%,治疗组为58.1%,两组比较,差异有统计学意义(P<0.05);治疗2个月后,对照组总显效率为53.1%,治疗组为87.1%,两组比较,差异有统计学意义(P<0.05)。结论:阿达帕林凝胶外用、中药泡洗联合阿维A胶囊治疗多发性跖疣的临床疗效肯定,安全性高。
OBJECTIVE: To observe the clinical efficacy and safety of adapalene gel for external use and traditional Chinese medicine in combination with Avia A capsule in the treatment of multiple plantar warts. Methods: Sixty-four patients with multiple plantar warts were randomly divided into two groups according to the order of their visits. The control group received 32 cases of topical gel adaption and Chinese herbal foam wash therapy. In the treatment group, 32 cases were treated with the control group Avi A capsule. In the treatment of the first month and the second month of observation of each time and at the same time record the affected area rash. Record the liver, kidney function and blood lipids in the treatment group at the end of treatment. The final clinical efficacy was compared between the two groups. Results: After 1 month of treatment, the total effective rate was 25.0% in the control group and 58.1% in the treatment group, with significant difference between the two groups (P <0.05). After 2 months of treatment, the total effective rate in the control group was 53.1% in the treatment group and 87.1% in the treatment group. The difference between the two groups was statistically significant (P <0.05). Conclusion: Adapalene gel for external use, traditional Chinese medicine foam combined with Avi A capsule for the treatment of multiple plantar warts, the clinical efficacy of certain, high safety.