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目的目的探讨B超测宫颈长度联合胎儿纤维连接蛋白(f FN)检测对早产的预测价值。方法选择在我院定期产检有先兆早产症状的单胎妊娠孕妇152例为研究对象,所有孕妇均接受B超测宫颈长度及f FN检测,f FN阳性与宫颈长度≤25mm为孕妇早产分界值,比较B超测宫颈长度与f FN检测、两者联合检查对早产的预测价值。结果结果 f FN检测在7d内、14d内、37周内的f FN阳性预测值分别为17.14%,37.14%,45.71%;f FN阴性预测值分别为100%、100%、95.12%。B超测宫颈长度预测早产的阳性预测值为83.33%;阴性预测值为87.50%;f FN测定联合宫颈长度预测早产的阳性预测值为97.30%,阴性预测值为100%。结论论f FN检测与B超测宫颈长度联合预测早产具有较高的阳性预测值及阴性预测值,且特异性、敏感性高,利于提高早产预测准确度。
Objective To investigate the predictive value of ultrasonography combined with fetal fibronectin (f FN) detection in preterm labor. Methods A total of 152 singleton pregnant women with threatened symptoms of preterm birth were enrolled in our hospital. All pregnant women underwent cervical ultrasonography and F FN detection. F FN positive and cervical length ≤ 25mm were the premature birth cut-off value of pregnant women, Compare the B-test cervical length and f FN test, the two combined test for predictive value of preterm birth. Results The f FN positive predictive values within 7 days, within 14 days and within 37 weeks were 17.14%, 37.14% and 45.71%, respectively. The f FN negative predictive values were 100%, 100% and 95.12%, respectively. The predictive value of cervical ultrasonography for predicting preterm delivery of B ultrasound was 83.33% and the negative predictive value was 87.50%. The positive predictive value of f FN combined with cervical length predicted preterm birth was 97.30% and the negative predictive value was 100%. Conclusions The combination of f FN test and B-test cervical length prediction of preterm delivery has high positive predictive value and negative predictive value, and it has high specificity and sensitivity to improve preterm labor prediction accuracy.