Study on the Antimicrobial Activity of Flavonoids in Clausena indica(Datz). Oliv. Fruits

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[Objective] To extract flavonoids from Clausena indica(Datz) .Oliv.fruits and study their antimicrobial activities.[Method] Microwave-assisted method was used to extract flavonoids,whose antimicrobial activities were determined by filter paper diffusion method and LB medium double dilution method.[Result] The concentration of concentrated flavonoids extracted from Clausena indica(Datz) .Oliv.fruits was 162.298 5 mg/ml,and flavonoids presented good antimicrobial activities against Staphylococcu saureus,Bacillus subtilis and Escherichia coli with the MIC of 20.29,40.58 and 81.15 mg/ml,but the antimicrobial activity against Mucor and Saccharomyces cerevisiae was not obvious.[Conclusion] The study could provide theoretical basis for further exploring and developing Clausena indica(Datz) .Oliv.resources and producing new,safe and high-efficient biopreservatives. [Objective] To extract flavonoids from Clausena indica (Datz). Oliv. Trials and study their antimicrobial activities. [Method] Microwave-assisted method was used to extract flavonoids, whose antimicrobial activities were determined by filter paper diffusion method and LB medium double dilution Method. The concentration of concentrated flavonoids extracted from Clausena indica (Datz). Oliv. fruits was 162.298 5 mg / ml, and flavonoids presented good antimicrobial activities against Staphylococcus salvus, Bacillus subtilis and Escherichia coli with the MIC of 20.29, 40.58 and 81.15 mg / ml, but the antimicrobial activity against Mucor and Saccharomyces cerevisiae was not obvious. [Conclusion] The study could provide theoretical basis for further exploring and developing Clausena indica (Datz) .Oliv.resources and producing new, safe and high- efficient biopreservatives.
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